{"id":16709,"date":"2026-04-12T18:06:30","date_gmt":"2026-04-12T15:06:30","guid":{"rendered":"https:\/\/www.hakanyanar.com\/services\/gastric-cancer-surgery-istanbul\/"},"modified":"2026-04-12T21:16:06","modified_gmt":"2026-04-12T18:16:06","slug":"gastric-cancer-surgery-istanbul","status":"publish","type":"page","link":"https:\/\/www.hakanyanar.com\/en\/services\/gastric-cancer-surgery-istanbul\/","title":{"rendered":"Gastric Cancer Surgery Istanbul"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"16709\" class=\"elementor elementor-16709 elementor-16558\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-331b3d9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"331b3d9\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ae2c1e4\" data-id=\"ae2c1e4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7faabe5 elementor-widget elementor-widget-html\" data-id=\"7faabe5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!DOCTYPE html>\r\n<html lang=\"tr\">\r\n<head>\r\n<meta charset=\"UTF-8\">\r\n<meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\r\n<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Raleway:wght@400;500;600;700;800&family=Cormorant+Garamond:ital,wght@0,400;0,600;1,400&display=swap\" rel=\"stylesheet\">\r\n\r\n<style>\r\n*, *::before, *::after { box-sizing: border-box; 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font-family: Raleway, sans-serif; line-height: 1.5; }\r\n<\/style>\r\n<\/head>\r\n<body>\r\n<div class=\"hy\">\r\n\r\n<div class=\"hy-hero\">\r\n  <span class=\"hy-eyebrow\">Oncological Surgery \u00b7 Istanbul<\/span>\r\n  <h1>Gastric <span>Cancer<\/span><\/h1>\r\n  <div class=\"hy-hero-sub\">Prof. Dr. Hakan Yanar \u2014 General Surgery & Oncological Surgery Specialist<\/div>\r\n  <p class=\"hy-hero-desc\">Gastric cancer treated with laparoscopic gastrectomy, D2 lymphadenectomy, perioperative chemotherapy and HIPEC for selected peritoneal disease.<\/p>\r\n  <div class=\"hy-badges\"><span class=\"hy-badge\">\ud83d\udd2c Laparoscopic Gastrectomy<\/span><span class=\"hy-badge\">\ud83e\uddec HIPEC Certified<\/span><span class=\"hy-badge\">\ud83d\udc8a D2 Lymphadenectomy<\/span><span class=\"hy-badge\">\ud83d\udcc4 50+ International Publications<\/span><\/div>\r\n<\/div>\r\n<div class=\"hy-bc\"><a href=\"\/en\/\">Home<\/a><span class=\"hy-bc-sep\">\u203a<\/span><a href=\"https:\/\/www.hakanyanar.com\/en\/services\/\">Conditions<\/a><span class=\"hy-bc-sep\">\u203a<\/span>Gastric Cancer<\/div>\r\n<div class=\"hy-body hy-cf\">\r\n\r\n<div class=\"hy-sidebar\">\r\n  <div class=\"hy-toc\">\r\n    <div class=\"hy-toc-title\">\ud83d\udccb \u0130\u00e7indekiler<\/div>\r\n    <a href=\"#what-is\">What is Gastric Cancer?<\/a><a href=\"#risk\">Risk Factors<\/a><a href=\"#symptoms\">Symptoms<\/a><a href=\"#staging\">Diagnosis & Staging<\/a><a href=\"#treatment\">Treatment<\/a><a href=\"#istanbul\">Surgery in Istanbul<\/a><a href=\"#faq\">FAQ<\/a>\r\n  <\/div>\r\n  <div class=\"hy-doc-card\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.hakanyanar.com\/wp-content\/uploads\/2022\/01\/hakanyanarliv-2.png\" alt=\"Prof. Dr. Hakan Yanar\" class=\"hy-doc-img\">\r\n    <div class=\"hy-doc-name\">Prof. Dr. Hakan Yanar<\/div>\r\n    <div class=\"hy-doc-title\">Genel Cerrahi & Onkolojik Cerrahi Uzman\u0131<\/div>\r\n    <a href=\"tel:+905301715814\" class=\"hy-doc-btn\">\ud83d\udcde Randevu Al<\/a>\r\n    <a href=\"https:\/\/wa.me\/905301715814\" class=\"hy-doc-btn wa\" target=\"_blank\">\ud83d\udcac WhatsApp<\/a>\r\n  <\/div>\r\n  <div class=\"hy-info-box\">\r\n    <div class=\"hy-info-title\">\u26a1 H\u0131zl\u0131 Bilgiler<\/div>\r\n    <div class=\"hy-info-row\"><span class=\"hy-info-label\">Operating Time<\/span><span class=\"hy-info-val\">3\u20135 hours<\/span><\/div><div class=\"hy-info-row\"><span class=\"hy-info-label\">Hospital Stay<\/span><span class=\"hy-info-val\">5\u20137 days<\/span><\/div><div class=\"hy-info-row\"><span class=\"hy-info-label\">Method<\/span><span class=\"hy-info-val\">Laparoscopic \/ Robotic<\/span><\/div><div class=\"hy-info-row\"><span class=\"hy-info-label\">Recovery<\/span><span class=\"hy-info-val\">3\u20134 weeks<\/span><\/div><div class=\"hy-info-row\"><span class=\"hy-info-label\">Stage I Survival<\/span><span class=\"hy-info-val\">70\u201390%<\/span><\/div><div class=\"hy-info-row\"><span class=\"hy-info-label\">Languages<\/span><span class=\"hy-info-val\">TR \u00b7 EN \u00b7 FR \u00b7 RU<\/span><\/div>\r\n  <\/div>\r\n<\/div>\r\n<div class=\"hy-content\">\r\n\r\n<div class=\"hy-sec\" id=\"what-is\">\r\n<h2>What is Gastric Cancer?<\/h2>\r\n<p class=\"hy-p\"><strong>Gastric cancer<\/strong> (stomach cancer) is a malignant neoplasm arising predominantly from the glandular epithelium of the stomach. Adenocarcinoma accounts for more than 90% of cases. It is the fifth most common cancer globally and the fourth leading cause of cancer mortality, with the highest incidence in East Asia, Eastern Europe, and parts of South America.<\/p>\r\n<p class=\"hy-p\">Gastric cancers are anatomically classified by location (cardia, body, antrum\/pylorus) and histologically by Lauren classification (intestinal vs. diffuse type). Molecularly, four subtypes are recognized by TCGA: EBV-positive, MSI, genomically stable (GS), and chromosomally unstable (CIN) \u2014 each with distinct prognostic and therapeutic implications.<\/p>\r\n<div class=\"hy-info-alert\"><p>\ud83d\udccc <strong>Key fact:<\/strong> Five-year survival exceeds 70% when gastric cancer is detected at Stage I. Eradication of H. pylori infection is the most effective preventive measure for intestinal-type gastric cancer.<\/p><\/div>\r\n<\/div>\r\n\r\n<div class=\"hy-sec\" id=\"risk\">\r\n<h2>Risk Factors<\/h2>\r\n<div class=\"hy-risk-grid\">\r\n<div class=\"hy-risk-item\"><div class=\"hy-risk-icon\">\ud83e\udda0<\/div><div class=\"hy-risk-title\">H. pylori Infection<\/div><div class=\"hy-risk-desc\">Helicobacter pylori is classified as a Group 1 carcinogen. Chronic infection leads to atrophic gastritis, intestinal metaplasia, and dysplasia \u2014 the premalignant cascade for intestinal-type gastric cancer.<\/div><\/div>\r\n<div class=\"hy-risk-item\"><div class=\"hy-risk-icon\">\ud83e\uddc2<\/div><div class=\"hy-risk-title\">Dietary Factors<\/div><div class=\"hy-risk-desc\">High salt intake, preserved and smoked foods, and nitrate-rich diets significantly increase risk. Conversely, fresh fruit and vegetable consumption \u2014 rich in antioxidants \u2014 is protective.<\/div><\/div>\r\n<div class=\"hy-risk-item\"><div class=\"hy-risk-icon\">\ud83e\uddec<\/div><div class=\"hy-risk-title\">Genetic Factors<\/div><div class=\"hy-risk-desc\">Hereditary diffuse gastric cancer (CDH1 germline mutation), Lynch syndrome, and familial adenomatous polyposis confer substantially elevated lifetime risk and require dedicated surveillance.<\/div><\/div>\r\n<div class=\"hy-risk-item\"><div class=\"hy-risk-icon\">\ud83d\udeac<\/div><div class=\"hy-risk-title\">Lifestyle Factors<\/div><div class=\"hy-risk-desc\">Cigarette smoking approximately doubles gastric cancer risk. Obesity is associated with gastroesophageal junction adenocarcinoma. Previous gastric surgery (Billroth II) modestly increases risk after 15\u201320 years.<\/div><\/div>\r\n<\/div>\r\n<\/div>\r\n\r\n<div class=\"hy-sec\" id=\"symptoms\">\r\n<h2>Symptoms & Warning Signs<\/h2>\r\n<div class=\"hy-warn\"><div class=\"hy-warn-title\">\u26a0\ufe0f Alarm Symptoms Requiring Urgent Endoscopy<\/div><p>Dysphagia, hematemesis, involuntary weight loss exceeding 10% of body weight, a palpable epigastric mass, or new-onset dyspepsia in a patient over 55 years of age require urgent upper GI endoscopy to exclude gastric malignancy.<\/p><\/div>\r\n<ul class=\"hy-ul\">\r\n<li>Persistent epigastric pain or discomfort not relieved by antacids<\/li>\r\n<li>Progressive dysphagia \u2014 particularly with proximal or cardial tumors<\/li>\r\n<li>Early satiety and postprandial fullness<\/li>\r\n<li>Nausea and vomiting \u2014 may indicate gastric outlet obstruction with antral tumors<\/li>\r\n<li>Involuntary weight loss \u2014 present in the majority of patients at diagnosis<\/li>\r\n<li>Hematemesis or melena \u2014 indicative of tumor ulceration or erosion<\/li>\r\n<li>Iron-deficiency anemia \u2014 occult bleeding from the tumor surface<\/li>\r\n<\/ul>\r\n<\/div>\r\n\r\n<div class=\"hy-sec\" id=\"staging\">\r\n<h2>Diagnosis & Staging<\/h2>\r\n<p class=\"hy-p\">Upper gastrointestinal endoscopy with multiple biopsies is the diagnostic standard. Staging workup includes CT of the chest, abdomen and pelvis; endoscopic ultrasound (EUS) for T and N staging; diagnostic laparoscopy to exclude peritoneal metastases before planned curative resection; and molecular profiling (HER2, PD-L1, MSI\/MMR) to guide systemic therapy.<\/p>\r\n<div class=\"hy-stage-strip\"><div class=\"hy-stage hy-stage-1\"><div class=\"hy-stage-num\">STAGE I<\/div><div class=\"hy-stage-desc\">Confined to gastric wall<\/div><div class=\"hy-stage-surv\">70\u201390%<\/div><\/div><div class=\"hy-stage hy-stage-2\"><div class=\"hy-stage-num\">STAGE II<\/div><div class=\"hy-stage-desc\">Regional extension<\/div><div class=\"hy-stage-surv\">45\u201365%<\/div><\/div><div class=\"hy-stage hy-stage-3\"><div class=\"hy-stage-num\">STAGE III<\/div><div class=\"hy-stage-desc\">Lymph node involvement<\/div><div class=\"hy-stage-surv\">20\u201340%<\/div><\/div><div class=\"hy-stage hy-stage-4\"><div class=\"hy-stage-num\">STAGE IV<\/div><div class=\"hy-stage-desc\">Distant metastases<\/div><div class=\"hy-stage-surv\"><10%<\/div><\/div><\/div>\r\n<p class=\"hy-p\">Survival data are approximate population-based estimates. Individual prognosis depends on tumor biology, molecular subtype, surgical quality, and access to multidisciplinary oncological care.<\/p>\r\n<\/div>\r\n\r\n<div class=\"hy-sec\" id=\"treatment\">\r\n<h2>Treatment<\/h2>\r\n<p class=\"hy-p\">Gastric cancer treatment requires multidisciplinary oncology board review. The integration of surgery, perioperative chemotherapy, and \u2014 in selected patients \u2014 targeted therapy or immunotherapy has substantially improved outcomes over the past decade.<\/p>\r\n\r\n<div class=\"hy-treat-card\">\r\n<div class=\"hy-treat-head\">\r\n<div class=\"hy-treat-icon\">\ud83d\udd2c<\/div>\r\n<div class=\"hy-treat-title\">Laparoscopic Gastrectomy \u2014 Oncological Standard<\/div>\r\n<div class=\"hy-treat-badge\">Standard of Care<\/div>\r\n<\/div>\r\n<div class=\"hy-treat-body\">\r\n<div class=\"hy-treat-stats\"><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">3\u20135 hrs<\/span><span class=\"hy-treat-stat-lbl\">Operating time<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">5\u20137 days<\/span><span class=\"hy-treat-stat-lbl\">Hospital stay<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">3\u20134 weeks<\/span><span class=\"hy-treat-stat-lbl\">Return to work<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">D2<\/span><span class=\"hy-treat-stat-lbl\">Lymphadenectomy<\/span><\/div><\/div>\r\n<p>Laparoscopic gastrectomy \u2014 either subtotal (distal) for antral tumors or total for body and proximal lesions \u2014 removes the tumor-bearing stomach with adequate margins and systematic D2 lymphadenectomy. D2 dissection, removing perigastric and hepatic\/splenic artery nodes, is the oncological standard associated with the best long-term survival.<\/p><p>Randomized trials confirm that laparoscopic gastrectomy achieves equivalent oncological outcomes to open surgery while offering significantly less postoperative pain, shorter hospital stay (5\u20137 days), reduced blood loss, and faster recovery. Prof. Dr. Hakan Yanar performs both subtotal and total gastrectomy laparoscopically.<\/p>\r\n<ul class=\"hy-treat-points\"><li>Oncological equivalence to open gastrectomy confirmed by RCTs<\/li><li>D2 lymphadenectomy as standard \u2014 \u226515 lymph nodes examined<\/li><li>Shorter hospital stay and faster recovery than open surgery<\/li><li>Robotic assistance available for complex resections<\/li><\/ul>\r\n<\/div>\r\n<\/div>\r\n\r\n<div class=\"hy-treat-card\">\r\n<div class=\"hy-treat-head\">\r\n<div class=\"hy-treat-icon\">\ud83d\udc8a<\/div>\r\n<div class=\"hy-treat-title\">Perioperative Chemotherapy \u2014 Locally Advanced Disease<\/div>\r\n<div class=\"hy-treat-badge\">Stage II\u2013III<\/div>\r\n<\/div>\r\n<div class=\"hy-treat-body\">\r\n<div class=\"hy-treat-stats\"><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">FLOT<\/span><span class=\"hy-treat-stat-lbl\">Standard regimen<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">4 cycles<\/span><span class=\"hy-treat-stat-lbl\">Pre-operative<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">4 cycles<\/span><span class=\"hy-treat-stat-lbl\">Post-operative<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">\u2191 R0 rate<\/span><span class=\"hy-treat-stat-lbl\">Downstaging benefit<\/span><\/div><\/div>\r\n<p>The FLOT4 trial established perioperative FLOT (docetaxel, oxaliplatin, leucovorin, 5-FU) as the current standard of care for resectable locally advanced gastric and gastroesophageal junction cancers. Four cycles are administered before and four after surgery, improving R0 resection rates and overall survival compared with epirubicin-based regimens.<\/p><p>For HER2-positive tumors, trastuzumab is added to platinum-based chemotherapy in the palliative setting (ToGA trial). MSI-H\/dMMR tumors show exceptional responses to immune checkpoint inhibitors (pembrolizumab, nivolumab).<\/p>\r\n<ul class=\"hy-treat-points\"><li>FLOT is the current international perioperative chemotherapy standard<\/li><li>Downstaging improves R0 resection rates<\/li><li>HER2-positive: add trastuzumab<\/li><li>MSI-H: exceptional response to immunotherapy<\/li><\/ul>\r\n<\/div>\r\n<\/div>\r\n\r\n<div class=\"hy-treat-card\">\r\n<div class=\"hy-treat-head\">\r\n<div class=\"hy-treat-icon\">\ud83e\uddec<\/div>\r\n<div class=\"hy-treat-title\">HIPEC \u2014 Selected Peritoneal Disease<\/div>\r\n<div class=\"hy-treat-badge\">Peritoneal Metastases<\/div>\r\n<\/div>\r\n<div class=\"hy-treat-body\">\r\n<div class=\"hy-treat-stats\"><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">CRS+HIPEC<\/span><span class=\"hy-treat-stat-lbl\">Combined procedure<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">41\u201343\u00b0C<\/span><span class=\"hy-treat-stat-lbl\">Perfusion temp.<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">Selected cases<\/span><span class=\"hy-treat-stat-lbl\">Patient eligibility<\/span><\/div><div class=\"hy-treat-stat\"><span class=\"hy-treat-stat-val\">Multidisciplinary<\/span><span class=\"hy-treat-stat-lbl\">Board decision<\/span><\/div><\/div>\r\n<p>In carefully selected patients with limited peritoneal metastases from gastric cancer or positive peritoneal cytology, cytoreductive surgery combined with HIPEC may be offered with curative or cytoreductive intent. Selection criteria include complete cytoreduction (CC-0\/1 score), good performance status, and absence of extra-abdominal disease.<\/p><p>Prof. Dr. Hakan Yanar is HIPEC-certified and performs the procedure at Liv Hospital Ulus. Each candidate is evaluated by the multidisciplinary oncology board before proceeding to CRS+HIPEC.<\/p>\r\n<ul class=\"hy-treat-points\"><li>Curative-intent option for selected peritoneal disease<\/li><li>HIPEC-certified surgeon in Istanbul<\/li><li>Multidisciplinary patient selection essential<\/li><li>Gastric cancer with positive peritoneal cytology may also benefit<\/li><\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n\r\n<div class=\"hy-sec\" id=\"istanbul\">\r\n<div class=\"hy-istanbul\">\r\n<h2>Gastric Cancer Surgery in Istanbul<\/h2>\r\n<p class=\"hy-p\">Prof. Dr. Hakan Yanar is an oncological surgeon with over 50 international peer-reviewed publications, specializing in gastric cancer surgery at Istanbul University Faculty of Medicine and Liv Hospital Ulus. International patients are seen in English, French, and Russian with full coordination support including appointment scheduling, diagnostics, accommodation, and translation.<\/p>\r\n<\/div>\r\n<\/div>\r\n\r\n<script type=\"application\/ld+json\">\r\n{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What is gastric cancer?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Gastric cancer is a malignant tumor arising from the gastric mucosa. Adenocarcinoma accounts for over 90% of cases. It remains the fifth most common cancer and the fourth leading cause of cancer-related death worldwide, with incidence highest in East Asia, Eastern Europe, and parts of South America.\"}},\r\n{\"@type\":\"Question\",\"name\":\"What causes gastric cancer?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Helicobacter pylori infection is the most important modifiable risk factor and is classified as a Group 1 carcinogen by the IARC. 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Compared with open surgery, it offers less postoperative pain, shorter hospital stay (5\u20137 days), faster recovery, and equivalent long-term oncological outcomes.\"}},\r\n{\"@type\":\"Question\",\"name\":\"What is neoadjuvant chemotherapy for gastric cancer?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Perioperative chemotherapy (e.g., FLOT regimen: docetaxel, oxaliplatin, leucovorin, 5-fluorouracil) is the standard of care for resectable locally advanced gastric cancer in Western guidelines. It downstages the tumor, increases R0 resection rates, and improves overall survival compared with surgery alone.\"}},\r\n{\"@type\":\"Question\",\"name\":\"When is HIPEC used in gastric cancer?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"HIPEC is considered in gastric cancer with limited peritoneal metastases or positive peritoneal cytology. It is performed simultaneously with cytoreductive surgery. Patient selection is critical and requires multidisciplinary oncology board review. Prof. Dr. Hakan Yanar is HIPEC-certified.\"}},\r\n{\"@type\":\"Question\",\"name\":\"What is the survival rate for gastric cancer?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Five-year survival is approximately 70\u201390% for Stage I, 45\u201365% for Stage II, 20\u201340% for Stage III, and less than 10% for Stage IV disease. Outcomes are strongly influenced by tumor location, histological subtype, HER2 and PD-L1 status, and surgical quality.\"}},\r\n{\"@type\":\"Question\",\"name\":\"Can international patients receive treatment in Istanbul?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. Prof. Dr. Hakan Yanar provides consultations in English, French, and Russian. Comprehensive coordination including appointment scheduling, diagnostic workup, accommodation, and translation services is available for international patients at Liv Hospital Ulus, Istanbul.\"}}]}\r\n<\/script><div class=\"hy-sec\" id=\"faq\"><h2>S\u0131k Sorulan Sorular<\/h2><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What is gastric cancer?<\/div><div class=\"hy-faq-a\">Gastric cancer is a malignant tumor arising from the gastric mucosa. Adenocarcinoma accounts for over 90% of cases. It remains the fifth most common cancer and the fourth leading cause of cancer-related death worldwide, with incidence highest in East Asia, Eastern Europe, and parts of South America.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What causes gastric cancer?<\/div><div class=\"hy-faq-a\">Helicobacter pylori infection is the most important modifiable risk factor and is classified as a Group 1 carcinogen by the IARC. Other risk factors include high salt and nitrate intake, smoking, family history, atrophic gastritis, intestinal metaplasia, and prior gastric surgery.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What are the symptoms of gastric cancer?<\/div><div class=\"hy-faq-a\">Early gastric cancer is typically asymptomatic. Advanced disease presents with epigastric pain or discomfort, dysphagia (difficulty swallowing, particularly with proximal tumors), early satiety, nausea, involuntary weight loss, iron-deficiency anemia, and hematemesis or melena.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What is laparoscopic gastrectomy?<\/div><div class=\"hy-faq-a\">Laparoscopic gastrectomy \u2014 either subtotal (distal) or total \u2014 removes the tumor-bearing portion of the stomach with adequate oncological margins and D2 lymphadenectomy. Compared with open surgery, it offers less postoperative pain, shorter hospital stay (5\u20137 days), faster recovery, and equivalent long-term oncological outcomes.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What is neoadjuvant chemotherapy for gastric cancer?<\/div><div class=\"hy-faq-a\">Perioperative chemotherapy (e.g., FLOT regimen: docetaxel, oxaliplatin, leucovorin, 5-fluorouracil) is the standard of care for resectable locally advanced gastric cancer in Western guidelines. It downstages the tumor, increases R0 resection rates, and improves overall survival compared with surgery alone.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">When is HIPEC used in gastric cancer?<\/div><div class=\"hy-faq-a\">HIPEC is considered in gastric cancer with limited peritoneal metastases or positive peritoneal cytology. It is performed simultaneously with cytoreductive surgery. Patient selection is critical and requires multidisciplinary oncology board review. Prof. Dr. Hakan Yanar is HIPEC-certified.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">What is the survival rate for gastric cancer?<\/div><div class=\"hy-faq-a\">Five-year survival is approximately 70\u201390% for Stage I, 45\u201365% for Stage II, 20\u201340% for Stage III, and less than 10% for Stage IV disease. Outcomes are strongly influenced by tumor location, histological subtype, HER2 and PD-L1 status, and surgical quality.<\/div><\/div><div class=\"hy-faq-item\"><div class=\"hy-faq-q\">Can international patients receive treatment in Istanbul?<\/div><div class=\"hy-faq-a\">Yes. Prof. Dr. Hakan Yanar provides consultations in English, French, and Russian. Comprehensive coordination including appointment scheduling, diagnostic workup, accommodation, and translation services is available for international patients at Liv Hospital Ulus, Istanbul.<\/div><\/div><\/div>\r\n\r\n<div class=\"hy-cta\">\r\n  <h3>Book a Gastric Cancer Consultation<\/h3>\r\n  <p>Contact Prof. Dr. Hakan Yanar for evaluation and a personalized treatment plan in Istanbul.<\/p>\r\n  <div class=\"hy-cta-btns\">\r\n    <a href=\"tel:+905301715814\" class=\"hy-cta-btn primary\">\ud83d\udcde Hemen Ara<\/a>\r\n    <a href=\"https:\/\/wa.me\/905301715814\" class=\"hy-cta-btn wa\" target=\"_blank\">\ud83d\udcac WhatsApp ile Yaz<\/a>\r\n    <a href=\"\/iletisim\/\" class=\"hy-cta-btn primary\">\ud83d\udcc5 Online Randevu<\/a>\r\n  <\/div>\r\n<\/div>\r\n<div class=\"hy-related\"><h3>\u0130lgili Hastal\u0131k ve Tedaviler<\/h3><div class=\"hy-related-grid hy-cf\"><div class=\"hy-related-card\"><div class=\"hy-related-icon\">\ud83e\uddec<\/div><div class=\"hy-related-name\">HIPEC<\/div><div class=\"hy-related-desc\">Peritoneal disease treatment<\/div><a href=\"\/en\/services\/hipec\/\" class=\"hy-related-link\">Detayl\u0131 \u0130ncele \u2192<\/a><\/div><div class=\"hy-related-card\"><div class=\"hy-related-icon\">\ud83d\udd2c<\/div><div class=\"hy-related-name\">Colorectal Cancer<\/div><div class=\"hy-related-desc\">Laparoscopic surgery<\/div><a href=\"\/en\/services\/colon-rectal-cancer\/\" class=\"hy-related-link\">Detayl\u0131 \u0130ncele \u2192<\/a><\/div><div class=\"hy-related-card\"><div class=\"hy-related-icon\">\ud83e\udd16<\/div><div class=\"hy-related-name\">Robotic Surgery<\/div><div class=\"hy-related-desc\">Minimally invasive technology<\/div><a href=\"\/en\/services\/laparoscopic-robotic-surgery\/\" class=\"hy-related-link\">Detayl\u0131 \u0130ncele \u2192<\/a><\/div><\/div><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/body>\r\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Oncological Surgery \u00b7 Istanbul Gastric Cancer Prof. Dr. Hakan Yanar \u2014 General Surgery &#038; Oncological Surgery Specialist Gastric cancer treated with laparoscopic gastrectomy, D2 lymphadenectomy, perioperative chemotherapy and HIPEC for selected peritoneal disease. \ud83d\udd2c Laparoscopic Gastrectomy\ud83e\uddec HIPEC Certified\ud83d\udc8a D2 Lymphadenectomy\ud83d\udcc4 50+ International Publications Home\u203aConditions\u203aGastric Cancer \ud83d\udccb \u0130\u00e7indekiler What is Gastric Cancer?Risk FactorsSymptomsDiagnosis &#038; StagingTreatmentSurgery in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":15980,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-16709","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.7 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Gastric Cancer Surgery Istanbul &#8212; Prof. Dr. Hakan Yanar<\/title>\n<meta name=\"description\" content=\"Gastric cancer treatment in Istanbul with laparoscopic gastrectomy and HIPEC. 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Cerrahi int\u00f6rnl\u00fc\u011f\u00fcn\u00fc University of Colorado Health Science Center, Denver Colorado\u2019 da tamamlad\u0131. Mecburi hizmetini 1995-1996 y\u0131llar\u0131 aras\u0131nda Isparta\u2019da, askerlik hizmetini Nisan 2000\u2019de Tunceli\u2019 de yerine getirdi. 1996 y\u0131l\u0131nda \u0130stanbul T\u0131p Fak\u00fcltesi Genel Cerrahi Anabilim Dal\u0131\u2019nda ba\u015flad\u0131\u011f\u0131 Genel Cerrahi ihtisas\u0131n\u0131 \u201cKolon anastomozlar\u0131nda skar dokusu olu\u015fumu ve latirojen ila\u00e7lar\u0131n etkisi\u201d isimli tez ile Haziran 2001\u2019 de tamamlad\u0131. \u015eubat 2006-\u015eubat 2007 aras\u0131nda University of Southern California Medical Center, Department of General Surgery, Los Angeles, ABD\u2019 de \u00e7al\u0131\u015ft\u0131. Primer cerrahi ilgi alan\u0131 gastrointestinal hastal\u0131klar, mide, kolon ve rektum kanseri ba\u015fta olmak onkolojik cerrahi olgular\u0131n laparoskopik tedavisi \u00fczerine odaklanm\u0131\u015ft\u0131r. \u201cRobotik Cerrahi\u201d ve \u201cCytoreductive surgery (CRS) and Hypertermic intraperitoneal chemotherapy (HIPEC) in Peritoneal Surface Malignancy\u201d sertifikalar\u0131na sahiptir. T\u00fcrk Cerrahi Derne\u011fi, Hepato-Pankreato-Bilier Cerrahi Derne\u011fi, \u0130stanbul Tabib Odas\u0131 \u00fcyesi, Ulusal Travma ve Acil Cerrahi Derne\u011fi ile Ulusal Endoskopik Laparoskopik Cerrahi Derne\u011fi y\u00f6netim kurulu \u00fcyesidir. Ulusal Travma ve Acil Cerrahi Dergisi\u2019nde yard\u0131mc\u0131 edit\u00f6rl\u00fck, European Society of Trauma and Emergency Surgery (ESTES) Emergency Section\u2019 da Chairman ve T\u00fcrkiye delegeli\u011fi g\u00f6revlerini yerine getirmektedir. 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Cerrahi int\u00f6rnl\u00fc\u011f\u00fcn\u00fc University of Colorado Health Science Center, Denver Colorado\u2019 da tamamlad\u0131. Mecburi hizmetini 1995-1996 y\u0131llar\u0131 aras\u0131nda Isparta\u2019da, askerlik hizmetini Nisan 2000\u2019de Tunceli\u2019 de yerine getirdi. 1996 y\u0131l\u0131nda \u0130stanbul T\u0131p Fak\u00fcltesi Genel Cerrahi Anabilim Dal\u0131\u2019nda ba\u015flad\u0131\u011f\u0131 Genel Cerrahi ihtisas\u0131n\u0131 \u201cKolon anastomozlar\u0131nda skar dokusu olu\u015fumu ve latirojen ila\u00e7lar\u0131n etkisi\u201d isimli tez ile Haziran 2001\u2019 de tamamlad\u0131. \u015eubat 2006-\u015eubat 2007 aras\u0131nda University of Southern California Medical Center, Department of General Surgery, Los Angeles, ABD\u2019 de \u00e7al\u0131\u015ft\u0131. Primer cerrahi ilgi alan\u0131 gastrointestinal hastal\u0131klar, mide, kolon ve rektum kanseri ba\u015fta olmak onkolojik cerrahi olgular\u0131n laparoskopik tedavisi \u00fczerine odaklanm\u0131\u015ft\u0131r. \u201cRobotik Cerrahi\u201d ve \u201cCytoreductive surgery (CRS) and Hypertermic intraperitoneal chemotherapy (HIPEC) in Peritoneal Surface Malignancy\u201d sertifikalar\u0131na sahiptir. T\u00fcrk Cerrahi Derne\u011fi, Hepato-Pankreato-Bilier Cerrahi Derne\u011fi, \u0130stanbul Tabib Odas\u0131 \u00fcyesi, Ulusal Travma ve Acil Cerrahi Derne\u011fi ile Ulusal Endoskopik Laparoskopik Cerrahi Derne\u011fi y\u00f6netim kurulu \u00fcyesidir. Ulusal Travma ve Acil Cerrahi Dergisi\u2019nde yard\u0131mc\u0131 edit\u00f6rl\u00fck, European Society of Trauma and Emergency Surgery (ESTES) Emergency Section\u2019 da Chairman ve T\u00fcrkiye delegeli\u011fi g\u00f6revlerini yerine getirmektedir. Elli uluslararas\u0131, 20 ulusal \u00e7al\u0131\u015fmas\u0131hakemli dergilerde yay\u0131nlanm\u0131\u015ft\u0131r. \u0130ki uluslararas\u0131, on ulusal kitap b\u00f6l\u00fcm\u00fc bulunmaktad\u0131r. \u00c7ok say\u0131da s\u00f6zl\u00fc ve poster sunumu, yurt i\u00e7i ve yurt d\u0131\u015f\u0131 panel ve sempozyum konu\u015fmalar\u0131 ger\u00e7ekle\u015ftirmi\u015ftir. \u0130ki uluslararas\u0131, \u00e7ok say\u0131da ulusal kitap b\u00f6l\u00fcm\u00fc yaz\u0131m\u0131 ve \u00e7evirisi bulunmaktad\u0131r. Ekim 2008\u2019 de Do\u00e7ent, Mart 2014\u2032te profes\u00f6r \u00fcnvan\u0131n\u0131 alan Prof.Dr. Hakan Yanar \u0130ngilizce bilmektedir. Evli, bir k\u0131z ve bir erkek \u00e7ocuk babas\u0131d\u0131r.","sameAs":["https:\/\/hakanyanar.com","https:\/\/www.facebook.com\/profdrhakantyanar","https:\/\/www.instagram.com\/prof.dr.hakanyanar\/","https:\/\/www.linkedin.com\/in\/prof-dr-hakan-yanar\/","https:\/\/x.com\/https:\/\/twitter.com\/htyanar","https:\/\/www.youtube.com\/channel\/UCE5s8CGZzB4o2Pr1bxXKNRQ"],"honorificPrefix":"Prof. Dr","honorificSuffix":"PhD","gender":"male","knowsAbout":["Cytoreductive surgery","Kolon ve rektum kanseri","Selim anorektal hastal\u0131klar (hemoroidal hastal\u0131k","anal fiss\u00fcr (makat \u00e7atla\u011f\u0131) ameliyats\u0131z tedavisi","perianal fist\u00fcl"]}]}},"_links":{"self":[{"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/pages\/16709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/comments?post=16709"}],"version-history":[{"count":3,"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/pages\/16709\/revisions"}],"predecessor-version":[{"id":16725,"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/pages\/16709\/revisions\/16725"}],"up":[{"embeddable":true,"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/pages\/15980"}],"wp:attachment":[{"href":"https:\/\/www.hakanyanar.com\/en\/wp-json\/wp\/v2\/media?parent=16709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}